Next-Generation Sequencing – Edinburgh Genetics

Next Generation Sequencing

Edinburgh Genetics create customised life science solutions, providing complex Next Generation Sequencing (NGS) services, as well as manufacturing and supplying a full range of innovative genetic research devices.

About

Next Generation Sequencing is a powerful tool enabling the sequencing of millions of DNA molecules simultaneously.

NGS is the most innovative technology to accurately sequence large portion of DNA. Where millions of genetic sequences can quickly be processed at astonishingly low rates.

Cost Effective

Time Efficient

Edinburgh Based

Research Experience

NGS Applications

Personalised Medicine

Personalised medicine initiatives are tailored to the molecular characteristic of each patient’s disease. With NGS driven diagnostics, clinicians can determine the selection of targeted treatments to achieve the best possible result.

Clinical Diagnostic

Rapid and low-cost sequencing is providing physicians with the tools needed to translate genomic information into clinically actionable results.

Genetic Disease

Advances in NGS technologies are a turning point in the research, diagnosis, and treatment of genetic disorders from cancer to raredisease. NGSchangesthe workflow of cancer treatment by screening patients for genetic analysis in the early stage, drastically reducing wait time, increases accuracy of prognosis, and ultimately successful treatment.

Pathogen Outbreak

Sequencing the genetic makeup of viruses, bacteria, and other microscopic organism quickly and accurately provides crucial data on how micros change and mutate over time, essential to the effective management of a potential pathogen outbreak.

Sequencing Services

At Edinburgh Genetics, we provide a full range of Next Generation Sequencing (NGS) life science research related services.

We work with governments, international organisations and corporations to provide innovative research in animals and plants.

Bioinformatics

We have developed and implemented pipelines for quality assessment and control, sequence alignment, genome assembly, metagenomics, transcriptomics, environmental genomics and functional genomics.

Bioinformatics is a discipline at the interface between biology, computing and statistics.

Application includes organismal biology, molecular biology and biomedicine.

Bioinformatics allow researchers to gain new insights from DNA, RNA and protein sequence data and related data at the molecular level through data storage, mining, analysis and graphical presentation.

NGS Panel Customisation

Different needs, different approaches

Our panels offer a complete solution from assay design through advanced bioinformatics analysis with different options for targeting gene of interest

Edinburgh Genetics custom gene panels provide targeted re- sequencing of any gene of interest via next generation sequencing (NGS), providing information on point mutations, insertions/ deletions (INDELs), copy number variations (CNVs), and gene rearrangements for specific genes of interest.

Advantages

Gene Panel Customisation are advantages in multiple applications

Cancer Treatment

Tumour DNA Sequencing

With customised gene panel, oncologist can screen cancer patients for tumour DNA sequences that captures the genetic mutation that is specific to each individual cancer patient. Oncologist can utilise existing knowledge of known mutation and target the effects of said mutation.

Accurate Diagnostic

Oncologist can diagnose a patient’s cancer more accurately with result obtained from the tumour’s genetic profiling by NGS. Gene Panel Testing result shows specific genetic alteration a cancer has, allowing the identification of biological behaviour drivers of this cancer.

Individualised Therapy

Targeted therapies are determined based on precise identification of geneticmutations. Withresults obtained from NGS test, oncologists can correlate knowledge of existing therapy to patient’s specific genetic mutation, tailoring targeted treatment plan to individual needs.

NGS is an innovative technology that redefines the understanding of cancer treatment from location-based diagnosis to an extensive insight of its DNA sequences. With a vast amount of existing cancer treatments, the correct identification of available medicine to inhibit tumour drivers and pathways is the crucial step in the next generation of cancer treatment.

Microbiology

Next Generation Sequencing is a powerful tool to accelerate the detection of pathogens.

Applications in Clinical Microbiology

Learn More

Download the Brochure to find out more about our innovative Next Generation Sequencing Service.