USING METAGENOMIC NEXT-GENERATION SEQUENCING TO EVALUATE THE COMPOSITION OF MICROBIOME IN PATIENTS WITH COVID-19
October 27th, 2021
Metagenomic Next-Generation Sequencing (mNGS) combines the offer of detection of early stages of emerging pathogens directly from clinical specimens and provides information on the microbiome composition of the patient. The latter provides a snapshot of the patient’s microbiome, offering a valuable insight into possible coinfections that may associate with disease progression and prognosis. Growing evidence has been found that the microbiome of the respiratory tract can have an impact on the health and disease progression in the patients, but most research has been focused on the interactions between different strains of bacteria. With that in mind, it may be possible to predict which patients are more likely to develop severe disease by analyzing their microbiome.