Next-generation sequencing (NGS) represents an efficient and reliable method to evaluate the contribution of both common and rare...

The emerging discipline of proteogenomics arose from the combination of two molecular biology fields – mass spectrometry (MS)-based...

Chemotherapy is often aggressive and can provoke severe toxicity and adverse drug reactions (ADR). Noticeable differences also exist in...

Although it is widely accepted that genetic testing is an important tool to aid early diagnosis in some patient cohorts, studies have...

Among the most researched pharmacogenes is the CYP gene superfamily (Fukunaga et al., 2021), which influences drug-metabolising enzymes...

Personalised diagnostic and precision medicine for cancer patients involves tailoring each patient’s treatment based on the genomic...

With the continuous discovery of genetic targets correlated with recurrence risk, time to recurrence (TTC) and/or overall survival, it is...

Among the most researched such genes are the ones belonging to the CYP gene superfamily, which is thought to cause up to 60% of...