Genetic Services

Using metagenomic sequencing to evaluate the composition of microbiome in patients with Covid-19

Metagenomic Next-Generation Sequencing (mNGS) combines the offer of detection of early stages of emerging pathogens directly from...

Exploring the HoloRuminant Microbiome

HoloRuminant is a global initiative aiming to elucidate the role of ruminant-associated microbiomes and their interplay with the host...

Working with the University of Gdansk in a landmark HTAD Treatment Trial

Marfan syndrome is a genetic disorder that affects the body's connective tissue, which provides strength, support, and elasticity to...

Insights into paleogenetics from NGS

While ‘modern’ humans are the only hominin species existing on the planet today, in the past our species has overlapped both temporally...

NGS in clinical histocompatibility testing

The human leukocyte antigen (HLA) region is one of the most researched parts of the human genome due to the fact multiple vital genes for...

Whole Exome Sequencing of Endangered Harlequin Frogs

In order to avoid extinction in a quickly changing environment, a species must adapt rapidly to avoid extinction. A group of researchers...

Visit from Princess Royal to the Pentlands Science Park

We were delighted and honoured to welcome Her Royal Highness The Princess Royal at the Pentlands Science Park to discuss our work in...

Genetic research and diagnosis of Endometriosis

Endometriosis is a gynaecological disease affecting around 10% of women of reproductive age. The main symptoms of endometriosis are pain...

Genome-first approach to mendelian cardiovascular disease

Since the 1990s cardiovascular genomics has been a popular area of research, heading toward a genome-first approach to the diagnosis and...

Chemotherapy, radiotherapy and adverse drug reaction mitigation using NGS

Chemotherapy is often aggressive and can provoke severe toxicity and adverse drug reactions (ADR). Noticeable differences also exist in...

The utility of low-depth Whole Genome Sequencing (WGS)

A human sample sequenced at 0.1x depth using 150 bp reads yields 2.2 million reads corresponding to measurements at 330Mbp. At 0.4x...

Proteogenomics, the role of NGS

The emerging discipline of proteogenomics arose from the combination of two molecular biology fields –mass spectrometry (MS)-based...